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  • Blood Pressure Monitor
    Blood pressure-lowering effect of Korean red ginseng associated with decreased circulating Lp-PLA2 activity and lysophosphatidylcholines and increased dihydrobiopterin level in prehypertensive subjects

    We evaluated the effects of red ginseng consumption on blood pressure (BP) and the fasting plasma metabolome. 



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    Nature hypertension research

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    Circulating Lp-PLA2 activity correlates with oxidative stress and cytokines in overweight/obese postmenopausal women not using hormone replacement therapy

    Controversy remains regarding whether there is an association between circulating lipoprotein-associated phospholipase A2 (Lp-PLA2), cytokines, and oxidative stress in healthy postmenopausal women. We investigated the influence of age on Lp-PLA2 activity in postmenopausal women not using hormone therapy and the relationship of Lp-PLA2 enzyme activity to serum cytokine levels and oxidative stress indices.



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    AGE

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    Apolipoprotein B: novel indicator of elevated intraocular pressure

    Many studies have reported associations between elevated intraocular pressure (IOP) and systemic health parameters, which suggest a common mechanism links IOP elevation and various related cardiometabolic risk factors. Furthermore, according to a recent study, serum apolipoprotein B (APO B) level is a predictor of coronary artery disease. This study was undertaken to analyse the relationship between serum apolipoprotein levels and IOP.



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    Nature Eye

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    Renal Hyperfiltration as a Novel Marker of All-Cause Mortality

    To elucidate the long-term clinical implications of RHF as a novel predictor of survival, we investigated the association between age-, sex-, muscle mass-, and history of diabetes and/or hypertension medication-adjusted RHF and all-cause mortality within a large adult population. We further examined the role of smoking on the association between RHF and mortality.



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    Journal of the American Society of Nephrology

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    Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients

    This study aimed to investigate the effects of gender on the association between epicardial fat thickness (EFT) and circadian blood pressure (BP) changes in patients with recently diagnosed essential hypertension (EH).



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    Journal of Diabetes Research

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    The triglyceride-lowering effect of supplementation with dual probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032: Reduction of fasting plasma lysophosphatidylcholines in nondiabetic and hypertriglyceridemic subjects

    This study evaluated the triglyceride (TG)-lowering effects of consuming dual probiotic strains of Lactobacillus curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 on the fasting plasma metabolome.



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    Nutrition, Metabolism and Cardiovascular Diseases

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    Effects of cold and hot temperature on dehydration: a mechanism of cardiovascular burden

    The association between temperature (cold or heat) and cardiovascular mortality has been well documented. However, few studies have investigated the underlying mechanism of the cold or heat effect. The main goal of this study was to examine the effect of temperature on dehydration markers and to explain the pathophysiological disturbances caused by changes of temperature. 



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    International Journal of Biometeorology

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    Association between the markers of metabolic acid load and higher all-cause and cardiovascular mortality in a general population with preserved renal function

    Although metabolic acid load has been associated with many well-known risk factors for mortality, its clinical implications are not yet clear. To evaluate the association between biomarkers of metabolic acid load, such as serum bicarbonate, serum anion gap and urine pH and mortality, we analyzed the health records of 31 590 adults who underwent a health screening between January 2001 and December 2010 and had an estimated glomerular filtration rate 60 ml min−1 per 1.73 m2.



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    Nature hypertension research

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    Visit-to-Visit Variability in Systolic Blood Pressure Is a Risk Factor for Rapid Loss of Residual Renal Function in Peritoneal Dialysis Patients

    Visit-to-visit systolic blood pressure variability (VTV-SBPV) is correlated with cardiovascular complications. However, it still remains unclear whether VTV-SBPV is related to cardiovascular outcomes in patients with peritoneal dialysis (PD), who often manifest hypertension. We, therefore, evaluated the association of VTV-SBPV with all-cause mortality, cardiovascular complications, or the loss of residual renal function (RRF) that is a powerful predictor of mortality and morbidity in PD patients.


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    The Tohoku Journal of Experimental Medicine

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    Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduces fasting triglycerides and enhances apolipoprotein A-V levels in non-diabetic subjects with hypertriglyceridemia

    Previous studies have indicated that supplementation with probiotics might improve lipid metabolism. The objective of the study was to evaluate the effect of supplementation with probiotic strains Lactobacillus curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 on triglyceride (TG) and apolipoprotein A-V (apo A-V) levels.



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    Atherosclerosis

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